Welcome to the PediPro video series, where real-world pediatric cases highlight clinical breakthroughs. In this 9th case, Dr. Pramod Jog presents a 5-year-old with respiratory distress, initially misdiagnosed as acute severe asthma. Despite standard therapy, the child showed no improvement until further testing confirmed Mycoplasma pneumonia. Treatment with azithromycin led to marked recovery. This case emphasizes the need for a high index of suspicion and careful differential diagnosis in pediatric respiratory conditions.