Welcome to the PediPro video series, where we explore the complexities of pediatric healthcare through expert case studies and clinical insights. In this 5th case study, Dr. Meenakshi Verma, a leading pediatrician, presents a compelling case on the intricate management of pediatric asthma compounded by adolescent obesity. The case, “Pediatric Asthma and Adolescent Obesity Management,” delves into the unique challenges of treating the obese-asthma phenotype—a condition marked by reduced treatment responsiveness and frequent exacerbations. Dr. Verma highlights the importance of a multidisciplinary approach that integrates respiratory care with metabolic health, using both pharmacologic strategies and behavioral interventions. Through this case, we witness the transformative impact of lifestyle modifications, family-centered counseling, and motivational interviewing in restoring asthma control and improving the quality of life for young patients. Tune in to explore evolving strategies in managing this dual burden of disease.