Welcome to the PediPro video series, where we explore the complexities of pediatric healthcare through expert case studies and clinical insights. In this 3rd case study, Prof (Dr.) Sunil Kumar Agarwal presents the diagnostic challenges of sarcoidosis in a pediatric patient, a rare multi-system granulomatous disease. The case of a 13-year-old boy, initially misdiagnosed, highlights the importance of early recognition and the value of a comprehensive, multi-disciplinary approach. Prof (Dr.) Agarwal underscores the significance of advanced diagnostic tools, including histopathological findings and elevated serum ACE levels, in reaching an accurate diagnosis. This case exemplifies the critical role of clinical vigilance and timely intervention in improving patient outcomes in rare pediatric conditions like sarcoidosis.