Welcome to the PediPro video series, where clinical insights meet real-world pediatric care. In this 13th case, Dr. Ashok Mittal shares the story of a 12-hour-old newborn presenting with severe respiratory distress soon after birth. Bedside echocardiography confirmed severe Persistent Pulmonary Hypertension of the Newborn (PPHN) with myocardial dysfunction. This case highlights the importance of early recognition, timely referral, multidisciplinary teamwork, and preparedness with advanced neonatal resources in rescuing critically ill newborns.